Albert Einstein is quoted as saying, "as our circle of knowledge expands, so does the circumference of darkness surrounding it." In other words, in expanding our awareness, we just expose our ignorance. The more we come to know, the more we realise we do not know.
This makes a lot of people uncomfortable. Astrophysicist and cosmologist Neil Tyson has described what many people do in response; instead of searching further, they build a wall around what they know so they do not have to see the darkness beyond.